A mouse cloning experiment that ran for two decades and spanned 58 generations of serial recloning has reached a dead end, ...

August Weismann's germ plasm theory of the late 19th century posited that only germ cells, e.g., sperm and egg cells in ...

Researchers at Oregon Health & Science University have accomplished a unique proof of concept to treat infertility by turning skin cells into eggs capable of producing early human embryos. The ...

Merck & Co. will apply the somatic genomics platform Quotient Therapeutics to discover novel drug targets in inflammatory bowel disease (IBD), through a collaboration that could generate up to $2.2 ...

Tsukuba, Japan—Animal organs are enclosed by a specialized epithelial layer. Epithelial cells typically exhibit apicobasal polarity: their apical surfaces contact other cells or the environment, ...

High-sensitivity sequencing of recurrent, cell-type–specific variants aims to strengthen causal inference versus germline ...

Generating gametes from nonreproductive tissues could help overcome infertility. Previous studies have successfully transformed stem cells into viable oocytes through cellular reprogramming.