RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells ...

Contrary to historic understanding of RNA’s longevity in cells, some RNAs can persist in cells throughout the life of an organism. Lead authors, Martin Hetzer, PhD, president of the Institute of ...

Ribonucleic acids (RNAs) are the ultimate cellular insiders. They perform several critical jobs, such as ferrying genetic instructions from a living organism’s DNA to its protein-making machinery (a ...

Neurons have a "hibernation mode." Scientists discover how brain cells use RNA tentacles to lock their protein factories together to survive when energy is low.

When RNA molecules are synthesized by cells — a critical process in the creation of proteins and other cellular functions — they typically undergo a series of “folding” events that determine their ...

Endogenous RNA is central to protein control and, ultimately, cellular function. Synthetic RNA is an important tool for biological research and is also offering a new generation of promising ...

Ribonucleic acid, commonly known as RNA, is involved in many biological functions, and some, including gene silencing, are utilitized to cure diseases. RNA has recently gained attention as a promising ...

The origin of life continues to remain a matter of debate. The ribonucleic acid (RNA) world hypothesis proposes that 'ribozymes' which store genetic information and possess catalytic functions may ...

A single intramuscular injection of a self-amplifying RNA therapy produced weeks of heart-protective protein in rat models of myocardial infarction, according to a study published in Science on March ...